Newsletter | September 22, 2025

09.22.25 -- CDMO Hunger Games And The State Of Biotech

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Webinar: Expert Roundtable: Real-World Process Intensification Strategies for Smarter Biomanufacturing

Discover how leading experts are using process intensification (PI) to cut costs, boost yield, and future-proof biopharma manufacturing. In this Sartorius webinar, gain practical insights on modernizing legacy facilities, implementing PI across upstream and downstream, and leveraging automation, digital tools, and modular upgrades. See real-world case studies proving how to deliver more—without building more. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

CDMO Hunger Games And The State Of Biotech

 Biotech leader Nicole Paulk, Ph.D., joins “Better Biopharma” to discuss Siren Biotechnology’s switch from plasmids to producer cell lines, CGT funding challenges, and the competition that determined which CDMO won Siren’s business.

Sensitive Residual E. coli DNA Testing In Biologics And CGT Development

Advancements in high-sensitivity residual DNA testing enhance the precision of plasmid DNA purity analysis, ensuring compliance with regulatory standards critical for manufacturing processes.

Enhance Productivity, Ensure Reliability: Shaking Incubator Proactive Service

Regular preventive maintenance is essential for ensuring the longevity and optimal performance of your shaking incubator. Find out how this approach helps avoid costly downtime and protects your research.

The Power Of 3: How Triple Stack Incubators Can Help Optimize Your Lab

Maximize your lab’s efficiency without sacrificing space. Discover how triple-stack incubators help scale operations, run multiple experiments, and streamline workflows within a compact footprint.

A Different Approach To Adeno-Associated-Virus (AAV) Clarification

Knowledge of the feed stream, process constraints, and goals, makes selecting depth and membrane filter combinations for preliminary bench-scale filterability studies possible.

N-1 Perfusion High Inoculum Fed-Batch For Reduced COGS And Easy Retrofit

Uncover how this company was able to triple productivity and cut costs by optimizing its seed train process to achieve major gains without infrastructure expansion.

From Black Box To Precision: A New Era Of Glycan Control

Glycoprotein therapies face variable glycan profiles. An alternative approach, IVGE, moves modification outside the cell for true molecular control, ensuring consistency and speed.

A Beginner's Guide To Sf9 Culture In Stirred-Tank Bioreactors

Learn about the workflow steps for Sf9 cell expansion, virus preparation, and protein production in stirred-tank bioreactors, including GFP expression.

Instant PAT Implementation Across Cell Lines, Media, And Scales

Explore how MAVERICK’s Raman-based technology delivers instant, reliable measurements of glucose, lactate, and biomass across diverse cell lines, media, and scales.

Rev-Up AAV Genome Production In Upstream Manufacturing

By increasing recombinant AAV titers, this AAV enhancer can help reduce upstream manufacturing costs and lower the cost per therapeutic dose.

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Webinar: Next-Generation MSC Therapies: Advancing Treatment for GvHD

Join this Corning Life Sciences webinar to explore an innovative approach for enhancing mesenchymal stromal cell (MSC) therapy in graft-versus-host disease (GvHD). Learn how genetically engineered Ad-MSCs co-expressing CXCR4 and IL-10 demonstrated superior migration, immune modulation, and therapeutic benefit in preclinical models. Plus, discover how Corning® HYPER technology enables efficient GMP-scale production for clinical applications. Register now to secure your spot! Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Produce High Cell Recovery Rates With The UniFuge UFMini - CARR Biosystems

Vertical-Wheel Bioreactor Product Guide - PBS Biotech, Inc.

Innovations In Transfection And Electroporation - Lonza

RoosterReplenish hMSC Bioreactor Feed - RoosterBio

CellShot Technology: Partitioned Flow Electroporation - Femtobiomed Inc.

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Webinar: Cell Bank & Scale Up Strategies for MSC & Exosome Manufacturing

This webinar explores two key decisions affecting the manufacturability and long-term success of advanced therapies. RoosterBio experts will share strategies for reducing costs, risks, and timelines in GMP manufacturing through optimized cell banking. Attendees will learn about major risk areas, effective banking strategies, and scale-up techniques for MSC and exosome production to support clinical and commercial success. Register here.

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