Cation Exchange & Anion Exchange Membranes: Natrix® HD Membrane Technology
Natrix HD Membranes offer a breakthrough in membrane architecture that will forever change downstream purification. Available in two chemistries: Q (strong anion exchange) and Sb (strong cation exchange and hydrophobic group).
With a revolutionary three-dimensional macroporous hydrogel structure that provides a High Density of binding sites and rapid mass transfer, Natrix HD Membranes deliver binding capacity that exceeds resin-based columns with fast flow rates typical of membrane adsorbers. Additionally, Natrix HD Membrane technology is highly versatile, and can be deployed in flow-through or bind-elute mode, with nearly any ion exchange, affinity or customized chemistry.
Natrix HD Membranes enable a number of performance gains across a wide range of chromatography. Key advantages include:
- Binding capacity equal to or better than the best column based resins.
- Flow rates as fast as the best membrane adsorbers.
- Compact, low-cost, single-use operation.
Binding Capacity:
Three-dimensional, macroporous structure of Natrix product produces a step-changes increase in binding surface areas and binding site density
High Throughput:
Unlike conventional beads that rely on diffusion, Natrix chromatography is dominated by advective flow, allowing flowrates up to 25x higher than conventional resin-based columns
Single Use:
Natrix products are compact and single-use, eliminating validation, cleaning, sanitization, and storage, while also enabling flexible, multi-use downstream processing
By combining the functionality of resin-base columns, the flowrates of membranes and single-use architecture, Natrix technology empowers a new level of downstream productivity and versatility.