Carl Zeiss Introduces Laser Scanning Microscope For Basic And Biomedical Research Applications

Thornwood, NY - Carl Zeiss MicroImaging Inc., a provider of microscopy solutions for a variety of research, clinical and industrial applications, introduces the LSM 710 NLO Laser Scanning Microscope. With the LSM 710 NLO L, Carl Zeiss provides basic and biomedical research with improved femtosecond multiphoton technology. This enables neurobiologists, developmental biologists, immunologists and plant biologists to examine complex biological systems without compromise.

The unique hallmarks of the LSM 710 NLO include the acquisition of high-resolution images of fluorescent structures in living animals and thick tissue specimens, long-time observation of development processes and functional imaging in combination with the photo manipulation of fluorescent structures. The high signal-to-noise ratio provided by the system ensures brilliant imaging of cellular and sub-cellular details even in deep-lying tissue layers. For the first time, up to five fluorescence signals can now be recorded simultaneously in what is called the non-descanned mode.

The basis of the new LSM 710 NLO system are extremely sensitive, non-descanned detectors for multiphoton microscopy, featuring optimized optics, electronics and detector positioning. Furthermore, a special version of the non-descanned detector with GaAsP technology and signal decoupling directly on the objective lens results in a greater increase to sensitivity. Depending on the microscope stand, up to five non-descanned detectors can be used with reflected and transmitted light and operated simultaneously.

Further benefits include the scanning module's optimized transmission over the entire wavelength range up to 1100 nm and the possibility of combining the multiphoton laser with any other laser line, including lasers with emission in the near UV range. As with the configuration of non-descanned detectors, the filters can also be combined by the customer as required. Complete integration of the system control into the ZEN 2008 software platform ensures efficiency and maximum specimen protection.

SOURCE: Carl Zeiss MicroImaging Inc.