Newsletter | October 6, 2025

10.06.25 -- Can CHO Bioreactors Be Used For Plant-Based Protein Production?

SPONSOR

Process: Intensified. Drug Manufacturing: Accelerated.

It’s never been more important to intensify — and with expert insight, cutting-edge solutions, and maximized value, it’s never been easier. Fast-forward your success with solutions that reduce complexity, cut time to market, and unlock greater potential at every step. Learn more here.

FOCUS ON UPSTREAM MANUFACTURING

Can CHO Bioreactors Be Used For Plant-Based Protein Production?

The moss Physcomitrium patens is especially good at producing glycoproteins. Established technology and prior knowledge are helping one company develop new therapies with it.

Facts About AAV Producer Cell Lines

Gene therapies are revolutionizing medicine, with AAV vectors leading the way. As production evolves, stable cell lines may replace transient transfection and unlock scalable solutions.

The Immortal Question: Can MSCs Be "Like A Cell Line But Not A Cell Line?"

Mesenchymal Stem Cells (MSCs) hold immense therapeutic promise. Can we harness their potential by making them more like consistent cell lines, without losing their unique advantages? Let's explore.

From Black Box To Precision: A New Era Of Glycan Control

Glycoprotein therapies face variable glycan profiles. An alternative approach, IVGE, moves modification outside the cell for true molecular control, ensuring consistency and speed.

A New Transfection System Tailored For Optimized AAV Production

In AAV manufacturing, long-term success depends not just on titers, but on maximizing the percentage of full capsids to ensure efficacy, safety, and scalability.

Cell Line Development For Bispecific Antibodies

See how the recently described cell line development paradigm shift, enabled by the Leap-In transposon platform, can extend to the development of bispecific monoclonal antibody-producing cell substrates.

What Every Scientist Should Know About Their Orbital Throw

Master orbital throw by understanding its impact on aeration, mixing, and growth. Explore recommendations for various applications and the benefits of adjustable throw incubator shakers.

Biocompatibility Studies On CHO Cell Culture In X-Ray Single-Use Bioreactors

In cell culture, the leakage of toxic or inhibitory chemicals from single-use bioreactors has become a growing concern. Explore recommendations for leachable studies.

SPONSOR

Webinar: Smart Media Screening & Design: Saving Time and Boosting Titers

Choosing the right culture medium is crucial after cell line development but can be challenging. Join this webinar to explore case studies, high-throughput screening, and strategies for selecting or designing optimal media and feed formulations—helping you save time, improve performance, and accelerate development. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Getting Started With Vertical-Wheel Bioreactors - PBS Biotech, Inc.

Flex Mixing System - Entegris, Inc.

CellThera Leads The Way: Innovation In Gamma Delta T Cell Media - ACROBiosystems

Innovation At Your Fingertips - MilliporeSigma

SPONSOR

Webinar: Developing your risk-based approach to single-use system integrity

This session explores best practices and evolving regulatory expectations for single-use system (SUS) integrity. Attendees will learn how to apply a holistic, lifecycle-based approach to compliance, define clear user requirements, and build robust contamination control strategies. By the end, participants will be prepared to safeguard efficiency and product quality while meeting regulatory and industry standards. Click here to learn more.

Connect With Bioprocess Online: