Bioprocessing Applications Lab (BPAL): A Partner-Focused Case Study In Solving Downstream Purification Challenges

Solve Downstream Purification Challenges with BPAL

See how Ecolab’s network of Bioprocessing Applications Laboratories (BPAL) combines specialized expertise, advanced development capabilities, and practical problem-solving to help overcome complex purification challenges.

When a biopharmaceutical organization encountered significant aggregation and low recovery in a monoclonal antibody purification process, Ecolab’s BPAL team developed a tailored downstream strategy designed around the needs of the molecule.

Utilizing high-throughput screening, chromatography development, and lab-scale confirmation, the team identified an optimized three-step purification workflow that improved recovery while dramatically reducing aggregation.

Explore the BPAL Case Study

See how BPAL can act as an extension of your process development team, providing the expertise, equipment, and experimental capacity needed to investigate challenging downstream purification problems.

In this case study, discover how BPAL helped:

• Increase product recovery by 41%
• Enable greater than 99% monomer purity
• Reduce process complexity and rework risk
• Develop a more robust purification strategy tailored to the molecule