Benefits Of Good Sample Preparation For The Bioanalytical Laboratory

When performing quantitative bioanalytical methods, there are many considerations to take when dealing with biological matrices and sample cleanliness. This presentation breaks down the common types of sample preparation and where the benefits can be added with the use of solid-phase extraction (SPE). Significant benefits to a bioanalytical method can be obtained by using SPE including:

• Reproducibility and robustness
• Increased sensitivity
• Removal of common matrix interferences
• Cleaner samples, instrumentation, and columns

Additionally, the webinar reviews how Oasis PRiME sorbents can help reduce the time needed for method development using simple 3- and 4- step SPE methods.

Key Learning Objectives:

• Recognize bioanalytical sample preparation types and the benefits of performing SPE
• Understand what common matrix interferences are and the importance of removal of phospholipids
• Know the difference between reversed-phase and mixed-mode SPE
• Learn about SPE methods that reduce time for method development on Oasis PRiME HLB and MCX