Avantor's PUPSIT (Pre-Use Post-Sterilization Integrity Testing) Assemblies

The Avantor® PUPSIT Assembly provides a dependable solution for meeting EU GMP Annex 1 requirements, which mandates pre-use post sterilization integrity testing (PUPSIT) to verify filter integrity before product filtration. This testing is essential to prevent contamination and ensure product sterility.

While PUPSIT design can be complex, this animation showcases how Avantor’s pre-designed PUPSIT assemblies can be easily configured and customized to your specific process. The solution simplifies implementation, minimizes contamination risk, enhances compliance, and enables early detection of filter flaws—ultimately supporting reliable final filtration, consistent product quality, and patient safety.