By Graeme Proctor, product manager (single-use technologies), Parker Bioscience Filtration, United Kingdom
The consequences of failure during downstream processing are severe. Following the Affinity Chromatography stage, the value of the product increases significantly at every step. A failure at the final bulk filling stage, therefore, could lead to the waste of millions of dollars’ worth of drug product.
It’s vital, therefore, to safeguard the bulk filling process. But traditional methods of conducting bulk fill operations have several disadvantages including manual handling, operator training, supply chain complexity, LAF maintenance and validation, shipping issues, and non-standard operations and process variability.
Learn how an automated and integrated single-use system for final bulk filtration can help you overcome those obstacles.