Automated Tissue Culture Cell Fixation And Staining In Microplates - Combination Washer Dispenser To Prepare Samples For Cellular Imaging

By Paul Held PhD and Bridget Bishop, BioTek Instruments, Inc.

Cellular imaging is becoming more important as a research tool in drug discovery and biomedical research. Low experimental sample numbers has historically allowed for manual implementation of the fixation and staining processes required prior to image analysis. However with the increased use of 96- and 384-well microplate formats the need for automating the sample preparation processes has become paramount. Here we describe the use of the EL406™ Combination Washer Dispenser to automate the fixation and staining processes typically used prior to imaging.