AUC As An Alternative For Biologics, Gene Therapy Characterization

Analytical Ultracentrifugation (AUC) is an advanced, highly adaptable technique that provides deep insight into the behavior of biomolecules in solution. By observing how molecules sediment under centrifugal force, AUC enables scientists to determine critical parameters such as size, aggregation state, molecular interactions, and sample heterogeneity. Because it analyzes molecules in their native environment without the need for labeling or immobilization, AUC offers unique advantages over many traditional analytical methods.

See how AUC can support the characterization of a wide range of therapeutic modalities, including biologics, peptides, vaccines, and gene and cell therapy vectors. Attendees will learn how sedimentation data can guide decision‑making during early development, help troubleshoot complex formulation challenges, and contribute to a deeper understanding of product quality attributes.

Participants will gain a clear understanding of the principles of AUC, the types of questions it can answer, and its emerging role across the development continuum.