Webinar | October 13, 2021

Application Of Two-Dimensional Chromatography To Improve Productivity Of Analytical Testing Of Cell & Gene Therapy Products

Analytical characterization of cell and gene therapy products remains a challenging, costly, and time-consuming task. Additionally, the relatively high sample volume typically required for analytical testing of such products is often considered as a challenge by itself. To overcome those issues, new technologies can be used, and in this video we present a proof-of-concept work demonstrating application of multidimensional chromatography for characterization of Adenovirus type 5 (Ad5)-based product.

The approach presented here not only allowed increased productivity, but also limits the sample volume needed for the analysis. We envision that by applying the concept presented in this proof-of-concept work, it will be possible to shorten the time necessary to perform analytical testing of CGT products and reduce the required volume of samples needed to complete the analysis.

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