Apoptosis Research Procapsase
Source: BIOMOL Research Laboratories, Inc.
Procapsase-3, designed for apoptosis research, has short N-terminal prodomains and is considered a downstream or effector procaspase...
Procapsase-3, designed for apoptosis research, has short N-terminal prodomains and is considered a downstream or effector procaspase. It can be cleaved and activated by "initiator" capsases, which are activated through interaction with death ligand receptor/adaptor protein complexes. Activation of the procapsase stands at a point of convergence for the two major types of apoptosis signaling pathway: those linked to cell-surface death-receptors and those linked to mitochondrial release of cytochrome-c.
BIOMOL Research Laboratories, Inc., 5100 Campus Drive, Plymouth Meeting, PA 19462-1123. Tel: 610-941-0430; Fax: 610-941-9252.
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