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Introduction To The 3 Pillars
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Many cell line development (CLD) workflows used today are highly manual and repetitive, and their processing steps leave little room for inconsistencies. These challenges, coupled with the industry’s increasing demand for greater output, have made accurate, comprehensive cell line characterization and cell culture screening more critical than ever.
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The industry lacks a device capable of rapidly and efficiently isolating single cells while maintaining their integrity and ensuring clonality. We demonstrate the use of an impedance-based single-cell dispenser combined with automated fluorescence-based high-throughput imaging to achieve monoclonal cell lines through reliable single-cell selection.
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Are you in the process of choosing your organization's automated colony-picking solution? Take an in-depth look at currently available microbial and mammalian clone screening devices and a comparison of various proven technologies. Further, explore topics including microbial colony picking, mammalian cell line development, and colony picking automation.
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Instruments and technologies supporting contemporary CLD workflows are more sophisticated than ever, creating more data points than can be feasibly processed by hand. Securely housing and managing this increasing data output necessitates strategies, software, and solutions that support an interconnected, interoperable process.
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Achieving analytical insights that enable decision-making is a key challenge for CLD laboratories. The analytical methods supporting a CLD workflow are often complex, and many of the most crucial insights are gained from instruments that are often large capital expenses or too challenging for most CLD personnel to operate easily.
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The diversity of workflows established by developers and laboratories has led to a proliferation of technologies designed to support cell line development campaigns. Advancements in these workflows have created the potential for greater standardization and automation, eliminating the most common workflow bottlenecks and improving reproducibility.
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