The mRNA Journey: From Design To LNP-Ready Molecules For Research

In vitro transcription (IVT) mRNA offers a powerful platform for rapid and robust protein expression in cells, making it a critical focus for developing vaccines and therapeutics. Achieving high quality and purity in your synthesized mRNA is non-negotiable for successful preclinical studies.

Learn a validated, end-to-end protocol for small-scale IVT mRNA production, covering everything from sequence design to formulation into lipid nanoparticles (LNPs). The approach includes simple techniques like PCR-based DNA template preparation and essential quality control checks, such as automated electrophoresis, to ensure integrity and yield. By mastering key design parameters and following this streamlined protocol, researchers can reliably generate high-quality mRNA for in vitro and in vivo applications in gene therapy, cell therapy, and vaccine development.

Discover how to streamline your mRNA journey for faster, more reliable preclinical results. Watch the full on-demand webinar to get the validated protocol.