Article | November 22, 2023

Advances In Protein A Chromatography

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Protein A resins have significantly improved over the past 30 years, yet even the most modern Protein A resins are not always amenable to newer IgG constructs. In many cases, these constructs are prone to aggregation, are acid labile, or otherwise sensitive to low pH. In this exploration of improvements in Protein A resins and process improvements in Affinity Chromatography, you will receive the answers to several questions posed by industry experts regarding Purolite’s novel resin, Praesto® Jetted A50 HipH.

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