AdvanceBio Your Oligonucleotide Workflow

Oligonucleotide characterization and purification require reliable separation of target sequences from closely related impurities, along with efficient method transfer as sample demands increase. Agilent’s integrated workflow combines AdvanceBio Oligonucleotide columns, LC instrumentation, software, standards, and supplies to support analytical, semi-preparative, and preparative applications. Scalable column chemistries help maintain selectivity while moving between workflows, and elevated pH and temperature stability can improve denaturing conditions and resolution. Automated data analysis supports sequence confirmation and impurity profiling, while flexible LC platforms enable fraction collection across a broad productivity range.

Explore practical options for improving purity, recovery, throughput, and consistency throughout the oligonucleotide workflow.