Achieving Optimal Purity And Recovery Of Monoclonal Antibodies Using Mixed-Mode Resins

In research, mAbs are common tools used in multiple techniques for the characterization of proteins and/or pathways due to their specificity and ease of use. They've shown efficacy and promise in treating diseases such as cancer, chronic inflammation, and infection.

In order to achieve optimal purity and recovery, the nature and downstream sequence of the polishing steps for any given mAb are customized based on multiple criteria. With mixed-mode resins, complementary chromatography methods are combined in a single resin and the process can be streamlined, resulting in a two-step workflow.

Learn about Nuvia cPrime Resin, Nuvia aPrime 4A Resin, and CHT Ceramic Hydroxyapatite Media along with how they can be used in chromatography and purification processes.