Achieving mRNA-LNP Delivery Beyond the Liver

What are the most promising R&D efforts or recent developments in the space that are paving the way for extra-hepatic delivery?

The rapid development, scale-up, and successful commercialization of mRNA vaccines served as a great case study on the important role mRNA/RNA therapeutics can play in society. However, for those striving to develop next-gen RNA therapeutics, achieving more specifically targeted non-viral delivery is a large hurdle to broadening these therapeutics’ applicability, durability, and effectiveness.