Achieving Full Control Over A Binary Blend Feeding A Liquid Chromatography Process Part 2

By Cory Hinz, Engineering Manager, Asahi Kasei Bioprocess America, Inc.

In liquid chromatography processes, the need for precise control of constituent blending continues with a focus on managing incoming process pressures to ensure reliable and repeatable operation. Variations in pressure from different sources or within a single batch can disrupt automated blending systems. To address this challenge, booster modules are introduced in front of each control valve, providing consistent and specific pressure.

These modules consist of three key components that safeguard against pressure fluctuations, bringing full control to the binary blend feeding into the liquid chromatography process. This process represents a crucial advancement in achieving precise control in liquid chromatography.