A Sustainable Future: Phasing Out Animal Testing

Phasing out animal testing in biologics safety is no longer a distant goal; it’s an actionable strategy. This application note explores a roadmap built on the internationally recognized 3Rs principles—Reduction, Replacement, and Refinement—plus a fourth: Responsibility. By categorizing tests into three baskets, it prioritizes mature alternatives like Next Generation Sequencing (NGS) and the Blazar® platform, while accelerating innovation for complex assays such as tumorigenicity and oncogenicity. It also highlights evolving regulatory guidance, including ICH Q5A and WHO recommendations, which increasingly endorse molecular methods over in vivo testing.

Learn how ethical responsibility, scientific innovation, and regulatory acceptance converge to create a sustainable future for biologics testing.