A Comprehensive Approach To Improving Solubility And Bioavailability: Spray Drying

Spray drying is a well-established manufacturing process with applications in foods, industrial products, and pharmaceuticals. Having come a long way from the first patent in 1865 (US patent 51,236),¹ spray dryers today support the development of some of the most advanced drug formulations, meeting the most precise morphological requirements to ensure performance, stability and manufacturability.

This article reviews stabilizing the amorphous form, an overview of the spray drying process, and how to keep an eye on the critical quality attributes of the product. We also explore comprehensive spray drying services from early development through commercialization, considerations for scale-up and technology transfer, analytical and downstream capabilities, and the benefit of a streamlined, comprehensive approach to spray drying.