Newsletter | September 28, 2026

09.28.26 -- 6 Modeling Approaches That Make Complex Bioprocess Data Useful

SPONSOR

 

Webinar: Accelerating CHO Media Development: From High-Throughput Screening to AI-Guided Design

Ready to rethink cell culture media development? Discover how high-throughput screening, process analytics, and AI-guided modeling can transform CHO media and feed optimization. This Thermo Fisher Scientific webinar explores ways to reduce experimental burden, navigate complex formulation spaces, and replace trial-and-error with faster, more predictive strategies. Gain practical insights to accelerate development and make smarter, data-driven decisions. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

6 Modeling Approaches That Make Complex Bioprocess Data Useful

AI algorithms can reduce data dimensionality more faithfully by interpreting multivariate features relevant to prediction or control.

 

 

Improving Bioprocessing Outcomes With An Elite Host Cell Line

Accelerate cell line development with a host engineered for high expression, streamlined clone selection, flexible gene integration, and scalable industrial performance.

 

The Scale-Up Of A Transient rAAV8 Production Process

New approaches to suspension cell culture and process scaling enable consistent, high-titer rAAV production. Gain insight into a clearer path to scalable manufacturing for gene therapy pipelines.

 

50-Color Spectral Cytometry Panel Links ICANS In Clinical Trials

Discover how integrated immune profiling reveals biomarkers and mechanistic insights into toxicity and treatment response, driving advances in cell therapy and personalized immunotherapy strategies.

 

The Proven, Practical Gateway To Upstream Process Intensification

N-1 perfusion enables higher inoculum densities, faster production, and reduced costs without altering fed-batch processes. Explore a practical path to intensification for biologics manufacturers.

 

From DNA To IND: Accelerated Development Backed By Experience

A rapid, integrated biologics development strategy can achieve IND readiness in as little as six months by combining parallel workflows, early risk mitigation, advanced technologies, and more.

 

The Power Of The Pool: Using Bulk Cultures For Clinical Trial Manufacturing

Stable bulk cultures, made highly uniform using transposase-mediated technologies, may be the key to expediting clone selection for many biopharmaceutical applications.

 

Uncoupling Yield And Glycosylation In Downstream Processing

See how in vitro glycoengineering uncouples glycosylation from fermentation variables, removing production compromises to safely optimize therapeutic protein yield and quality.

 

Overcoming Challenges To The Commercialization Of Therapies

Review the results obtained for our proprietary HEK293T 2G7 suspension cell line for LVV production by transient transfection in serum-free, chemically-defined and animal component-free media.

 

Scalable iPSC Differentiation To Natural Killer Cells With Cytotoxic Potential

Uncover an innovative serum-free method to differentiate induced pluripotent stem cells (iPSCs) into natural killer (NK) cells, offering scalable solutions for immunotherapy with enhanced cytotoxic potential.

 

Take The Turbulence Out Of Your Transfections

Run-to-run AAV titer variability can jeopardize production. Controlling incubation timing, DNA input, and media conditions improves yield and batch consistency.

 

Accelerating Cell Therapy Discovery With High-Throughput Electroporation

Delve into how high-throughput electroporation-based screening can compress your CAR-T optimization timeline while delivering reproducible, scale-ready results across multiple donor samples.

UPSTREAM MANUFACTURING SOLUTIONS

•

Bioprocess Equipment For Commercial Manufacturing - Eppendorf SE

•

Maintaining Contamination-Free Cell Cultures In Open-Vessel Cultivation - INFORS HT

•

Equipment Service Solutions - Cytiva

•

Microbiological Cooled Incubator - PHC Corporation of North America

•

Efficient Production Of MSCs And Exosomes - Terumo BCT

•

Formulation Unit: Automated Sampling And Final Formulation - Miltenyi Biotec

•

Accelerate Development With CHO-MK Platform Media - FUJIFILM Biosciences

Connect With Bioprocess Online: