Biomanufacturing White Papers and Case Studies
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Lipid Nanoparticle Compositional Analysis By UHPLC-CAD
6/30/2023
Explore results generated from an internal study using a proprietary mRNA-LNP formulation and UHPLC-CAD, a powerful technique for the analysis of compounds that do not contain chromophores.
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E. coli Fermentation Process Analysis With A Bioprocess Autosampler
6/22/2023
Learn the details and result of an autosampler and bioreactor pairing that was used for the sampling of eight parallel fermentation runs and for storing the samples in a cooling stack.
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Expectations On The Pathway To GMP For Gene-Modified Cell Therapies
6/21/2023
Learn how a robust understanding of the RNP’s critical process parameters and CQAs is crucial for ensuring product consistency, enhancing patient safety, and maintaining regulatory compliance.
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Digital Transformation: A Critical Component For CDMOs
6/21/2023
Learn how embracing the digital transformation is key for managing complexity of speed, service, quality, regulatory compliance, and capacity as well as the obstacles facing CDMOs looking to innovate.
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Establishing Analytical Methods For mRNA-Based Therapies
6/13/2023
Here, we provide a detailed description of assays for sequence identification and LNP composition in mRNA-LNP products that support the development of safe and effective mRNA therapies.
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Pharma Research, Development, & Launches Save Lives — & The Earth
6/1/2023
Understand how a defined framework and way of measuring allows companies to align priorities, short- or long-term goals, and what ESG success looks like.
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CRISPR RNPs And The Future Of Cell And Gene Therapy
4/21/2023
Explore the potential of ribonucleoprotein (RNP) to deliver CRISPR materials more accurately, efficiently, and effectively, as well as the manufacturing challenges which require further attention.
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Cold-Wall Or Convection? Critical Considerations For Application Selection
4/18/2023
Explore traditional cold-wall and convection technology to determine which best suits your cold needs for upcoming projects.
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Addressing New Challenges In Bulk Drug Substance Management
3/21/2023
The first line of defense against cold chain failures is the integrity of freezing containers during storage and shipping. Explore "robust by design" single-use solutions in cold chain management.
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Reduce Supply Chain Disruptions With Second Sourcing
3/16/2023
Follow one CDMO's collaboration with Thermo Fisher Scientific to combat supply chain risks after one of the high-volume raw materials critical to their manufacturing process experienced a global shortage.