Bioprocessing Application Notes & Case Studies
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Sterilizing Grade Filter Performance With Biologic Drugs
3/11/2024
Here, we analyze the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins and demonstrate how filter selection can impact your process.
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Aggregate Removal From mAbs By Hydrophobic Interaction Chromatography
3/7/2024
Review the results of a study where Hydrophobic Interaction Chromatography (HIC) techniques were used with a resin for the removal of aggregates in the manufacturing of monoclonal antibodies.
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Analysis Of Drug-Excipient Incompatibility In Discovery And Formulation Development
3/7/2024
We analyze drug-excipient incompatibility using a microcalorimeter system equipped with a multi-sample cell capable of simultaneously measuring highly sensitive heat flow data from up to three samples.
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Exosome Isolation By TFF And Size Exclusion Chromatography
3/6/2024
Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.
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Novel Engineered Plasmids, Optimized HEK293 Cell Line For AAV Productivity
3/5/2024
Lonza has further improved its platform process with the creation of engineered plasmids that afford significantly higher titers and productivity levels compared to standard systems.
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Meet An Optimized Suspension-Based Platform Technology
3/5/2024
Discover a ready-to-use, suspension-based platform technology for transient transfection of LVVs that eliminates the need to transition from small-scale adherent processes.
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Global BioPharma Saves Reporting Time On ADA Studies
2/29/2024
A flexible solution to save study reporting time has been achieved with a seamless integration with E-WorkBook and the customer’s LIMS.
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Leveraging Droplet Digital PCR For Accurate Viral Titer Measurement
2/29/2024
Accurately measuring viral titer is a key metric throughout gene therapy development, whether you are in the early stage, scaling production, or running assays for quality control release.
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Using GPS Engineering To Optimize Antibody-Based Drug Development
2/28/2024
Explore the results collected when a platform designed with ML-guided GPS engineering was applied to develop a lead molecule targeting a mechanism in neuronal disease.
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Characterization Of Host Cell Proteins By Liquid Chromatography - Mass Spectrometry
2/26/2024
Explore an established liquid chromatography – tandem mass spectrometry (LC-MS/MS) method for characterization of residual HCPs in monoclonal antibody (mAb) products.