Bioprocessing Application Notes & Case Studies
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Bulk Filling Of Drug Substance | Accurate Aliquoting
4/24/2024
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing
4/24/2024
Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.
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Sf9 Cell Suspension Culture In CorningĀ® Insect Cell Serum-Free Medium
4/22/2024
Explore the information gathered when the growth of Sf9 insect cells was studied in three different mediums.
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Vero Cell Culture In CorningĀ® Dry Powder Vero Serum-free Medium
4/22/2024
This study compares a serum-free medium to other commercially available pre-hydrated media to measure it's effectiveness in supporting the culture of adherent Vero cells.
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Transferring From Microfluidics To A Turbulent Mixer
4/18/2024
What solutions did the client featured in this case study find when they sought help in transferring their formulation process to a turbulent Impinged Jet Mixing (IJM)?
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Achieving a 21-Fold Increase in Plasmids
4/17/2024
This study compares a plasmid production process using differing shaker flasks to assess the cultivation similarities and contrasts, as well as total plasmid yields after plasmid purification.
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Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
4/17/2024
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression.
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Bakuchiol Synthesis Optimization In S. Cerevisiae During Scale Up From 250mL To 5L
4/15/2024
Explore the significance of cost-effectiveness in synthetic biology and the successful scaling up of a process involving S. cerevisiae for the production of bakuchiol.
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Simplifying CHO Cell Line Genetic Stability Testing
4/11/2024
Here, we describe the use of whole genome sequencing to perform a comprehensive assessment of genetic stability in clonally derived CHO cell banks using the Aptegra™ CHO genetic stability assay.
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Scaling Up mAb Process Development To A 5L Bioreactor
4/10/2024
This study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, showcases this technology transfer by comparing results obtained from shake flask cultures at various scales.