Single Use Featured Articles

  1. An Economic Microbial Fermentation Comparison Between Single-Use VS. Stainless Steel Equipment
    8/9/2016

    In this white paper, we compare production capacity and process economy between stainless steel and single-use equipment in microbial processes. Economy simulations were based on an E. coli Dab process. Production scenarios in both single- and multi-product facilities were considered.

  2. Accelerating Biopharmaceutical Development From DNA To Drug
    7/8/2016

    The pipeline of biopharmaceutical drugs is rich and becoming increasingly diverse. Many new biologic modalities are being developed as established therapeutic classes move through their lifecycle. Wide arrays of different types of molecules are expected to coexist within product portfolios and manufacturing networks. It is clear that this will have a significant impact on manufacturing facilities. Strategies need to be developed to prepare facilities for these challenges.

  3. Implementing Single-Use At Bioprocessing’s Core
    5/20/2016

    Expansions and renovations to existing biological facilities, and construction of new facilities, provide a unique opportunity to rethink basic design strategies and use new technologies to build a better facility that will improve compliance. One of the biggest drivers in the current evolution of biological facility design is the implementation of single-use systems (SUS).

  4. The Standardization Of Single-Use Components For Bioprocessing
    1/20/2016

    As single-use systems become more widely adopted, the focus in the bioprocessing industry is shifting from acceptance of the technology to standardization. While the standardization discussion encompasses many topics (including how products are tested, assembled, etc.), components are a critical area for improvement. With so many ways to apply single-use and hybrid bioprocessing systems, organizations must take action to standardize equipment in order to streamline operations and help reach the full potential of the technology.

  5. Single-Use Standardization: Is It Holding Back The Biopharma Industry?
    6/1/2015

    The data from BioPlan Associates’ 12th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production speaks to the industry’s ongoing desires for standardization in single-use devices. As usage of these disposable devices increases, the gap between the importance of standardization and end-users’ satisfaction with their supplier’s standardization efforts has steadily been worsening. 

  6. Gaining Efficiency Through Faster Integration of Single-Use Products
    9/24/2013

    Considered a full-service integrator of products in the biopharmaceutical industry, Saint-Gobain offers an online platform that improves their efficiencies to design single-use products by creating a 3-dimensional product drawing.

  7. Comparison Of Air-Wheel Bioreactor Against The Traditional Stirred-Tank Bioreactor in Microcarrier Applications
    1/29/2013

    A novel bioreactor system from PBS Biotech utilizes the patented Air-Wheel technology to promote uniform and homogenous liquid mixing and offers a low shear  environment for cell culture.

  8. Single-Use Budgets In 2013: Biotech Industry Council Indicates Industry Will Expand Spending On Key Products
    1/18/2013

    Disposable products continue to be a hot topic in biomanufacturing, as they increasingly penetrate clinical- and commercial-stage manufacturing and are sought after for their process efficiencies. In fact, when we asked the 450 global subject matter experts and senior participants on our Biotechnology Industry Council™ to identify the critical trends in bioprocessing for 2013, 22% cited aspects associated with implementation of single-use system integration.  These ranked narrowly behind need for downstream processing optimization, and analytical methods development (each at 24%). By Eric Langer, president and managing partner, BioPlan Associates, Inc.

  9. Meeting BioPharma Needs For Lower Operating Cost And Faster Time To Market
    11/28/2012

    Broad adoption awaits fully scalable GMP systems, improved and less costly disposables, better analytics, greater process automation and low-shear mixing.

  10. Budgets For Single-Use Systems On The Rise; CMOs The Biggest Spenders
    8/27/2012

    Single-use systems are rapidly becoming mainstream in the biopharmaceutical industry, even in commercial manufacturing.  Results from our 9th Annual Report and Survey of Biopharmaceutical Manufacturers indicate that budgets for single-use components are also on the rise, meaning this trend is likely to continue. By Eric Langer, President and Managing Partner, BioPlan Associates, Inc.