Single Use Featured Articles

1. Maintaining Bag Integrity In International Shipments
   12/2/2014

   The purpose of conducting this transportation simulation was to determine the integrity characteristics of one unitized load when exposed to conditions representative of shipping and handling stresses likely to occur during a product’s life cycle.

2. Gaining Efficiency Through Faster Integration of Single-Use Products
   9/24/2013

   Considered a full-service integrator of products in the biopharmaceutical industry, Saint-Gobain offers an online platform that improves their efficiencies to design single-use products by creating a 3-dimensional product drawing.

3. Comparison Of Air-Wheel Bioreactor Against The Traditional Stirred-Tank Bioreactor in Microcarrier Applications
   1/29/2013

   A novel bioreactor system from PBS Biotech utilizes the patented Air-Wheel technology to promote uniform and homogenous liquid mixing and offers a low shear  environment for cell culture.

4. Single-Use Budgets In 2013: Biotech Industry Council Indicates Industry Will Expand Spending On Key Products
   1/18/2013

   Disposable products continue to be a hot topic in biomanufacturing, as they increasingly penetrate clinical- and commercial-stage manufacturing and are sought after for their process efficiencies. In fact, when we asked the 450 global subject matter experts and senior participants on our Biotechnology Industry Council™ to identify the critical trends in bioprocessing for 2013, 22% cited aspects associated with implementation of single-use system integration.  These ranked narrowly behind need for downstream processing optimization, and analytical methods development (each at 24%). By Eric Langer, president and managing partner, BioPlan Associates, Inc.

5. Meeting BioPharma Needs For Lower Operating Cost And Faster Time To Market
   11/28/2012

   Broad adoption awaits fully scalable GMP systems, improved and less costly disposables, better analytics, greater process automation and low-shear mixing.

6. Moving Ahead With Single Use Technology
   9/5/2012

   This paper discusses the advantages of single-use vessel, bioreactor and mixing technologies, why they continue to grow in popularity for the bioprocessing market, and how to effectively overcome challenges in implementation of the technologies. By Richard Bhella

7. Budgets For Single-Use Systems On The Rise; CMOs The Biggest Spenders
   8/27/2012

   Single-use systems are rapidly becoming mainstream in the biopharmaceutical industry, even in commercial manufacturing.  Results from our 9th Annual Report and Survey of Biopharmaceutical Manufacturers indicate that budgets for single-use components are also on the rise, meaning this trend is likely to continue. By Eric Langer, President and Managing Partner, BioPlan Associates, Inc.

8. Biomanufacturers Looking For Single-Use Innovations
   7/9/2012

   Single-use innovation continues to be a hot topic, according to results from our 9th Annual Report and Survey of Biopharmaceutical Manufacturers. In fact, disposable products account for three of the top five new product development areas of interest this year among the 302 biomanufacturers we surveyed (the study evaluated 21 different new product areas).  By Eric Langer, President and Managing Partner, BioPlan Associates, Inc.

9. Single-Use Technologies Used Less For Downstream Purification Issues: Interest In Specific Technologies Remains Relatively Steady
   4/24/2012

   Downstream operations continue to create challenging bottlenecks and capacity problems. To identify what the industry is doing to address these bottlenecks, we asked 302 biopharmaceutical manufacturers in our 9th Annual Report and Survey of Biopharmaceutical Manufacturers about the specific areas their facility has actually implemented to improve their downstream purification (DSP) operations. By Eric Langer, president and managing partner, BioPlan Associates, Inc.

10. Helium Integrity Testing
    3/15/2012
    Single-use manufacturing technologies have made significant inroads into the bioprocessing market in recent years, as companies recognize the advantages they offer in terms of saving time and money, and reducing the risks of contamination from one batch to another. By Richard Bhella, ATMI