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FOCUS ON DOWNSTREAM MANUFACTURING |
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By Brian Glass, Pharmatech Associates — a USP company | Plasmid DNA (pDNA) is used in gene therapies, vaccines, and RNA therapeutics. Along each step of development, we need to evaluate potential impurities. |
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| 7 Facts About Antibody Drug Conjugates | Article | By Brian Moloney, Single Use Support | Take a look at how antibody drug conjugates are advancing oncology therapeutics and explore seven facts about them you probably didn't know. |
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| Optimize mAb Purification Using Protein A Membrane Chromatography | Poster | By M. Marinova, A.C. Lyons, M. DeVore, S. Madasu, M.C. Kerzic, and C.A. Mitchell, W.L. Gore & Associates | Discover how high throughput (HTP) screening can utilize membrane chromatography at comparable consumables costs to traditional resins without compromising CQAs for prescribed therapeutics. |
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| AAV Process Intensification With High Salt Lysis | Application Note | MilliporeSigma | In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity. |
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DOWNSTREAM MANUFACTURING SOLUTIONS |
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