CULTURE DEVELOPMENT FEATURED ARTICLES
Hear from Acepodia CEO Sonny Hsiao about his company's claims that its proprietary approach to conjugating novel natural killer cells could reduce the cost of cellular therapeutics.
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ISPE Announces Recruitment Milestone Achieved for Its Quality Metrics Pilot Program
ISPE announced today that its Quality Metrics Pilot Program has achieved a major milestone with confirmation of 12 companies and 32 sites participating in the Program, even as recruitment continues.
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Scientists ‘Snip’ HIV From Cultured Human Cells
Scientists from Temple University reported that they have designed a new approach to remove HIV from human cells growing in culture through genome editing.
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Stainless Steel Vial Filling System Developed For Use In Vaccine Facilities
TAP Biosystems (now part of the Sartorius Stedim Biotech Group), a leading supplier of innovative cell culture and fermentation systems for life science applications, recently announced the development of a stainless steel version of the fill-it system, designed for safely dispensing biohazardous materials such as vaccine stocks.
CULTURE DEVELOPMENT WHITE PAPERS & CASE STUDIES
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Wireless Dose-Compliance Monitoring In Drug-Delivery Devices
Incorporating wireless technology into medical devices is about more than just keeping up with the hottest technology trends; the benefits are real and significant, especially with regard to monitoring and encouraging dose compliance in the pharmaceutical and medical realm. Prior to embarking on the development of a wireless-enabled drug-delivery device, however, it is crucial to know what, specifically, the benefits are, and exactly what kinds of challenges and design considerations must be taken into account.
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Optimizing Methods In Microtissue Cultivation
Cells grown in standard suspension or monolayer culture lose many features that are characteristic of cells in tissues and limit their use to study certain aspects of cell biology.
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The Client Experience—Key to a CDMO’s Success
In the dynamic contract development and manufacturing organization (CDMO) industry, client-focused businesses succeed in retaining and growing our client base by delivering on project objectives and satisfying a client’s expectations.
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Adaption Of The BioLector Technology To Anaerobic Requirements
Biorefineries have reignited interest in anaerobic fermentations with biobutanol production being the principle driver. Already during the First World War Biobutanol and acetone were produced in Clostridium acetobutylicum.
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Live Cell Imaging Of GPCR Dependent Second-Messenger Systems
A significant proportion of academic and drug discovery research is devoted towards the elucidation of second messenger signaling cascades resulting from interactions between G-protein coupled receptors (GPCR) and their ligands. By Paul Held Ph. D. and Peter Banks, Ph. D., BioTek Instruments, Inc. and Paul Tewson, Anne Marie Quinn and Thom Hughes, Montana Molecular
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A Homogeneous Assay To Quantify Endogenous AKT Phosphorylation In Human Umbilical Vein Endothelial Cells
AKT is a serine/threonine protein kinase that plays a key role in cellular processes. AKT has become a popular target for drug discovery campaigns, due to the fact that AKT inhibitors may help to treat a number of cancers.