Single Use Featured Articles
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Safety, Containment, Filtration Efficiency And Energy Conservation Make The Paramount® Ductless Enclosure A Viable Alternative To A Ducted Fume Hood
1/30/2009
Safety is the primary purpose of any filtered enclosure or ventilated fume hood. In most situations, fume hoods remain the equipment of choice for ventilating hazardous airborne chemicals from the laboratory. However, there are applications where a ductless enclosure or ductless hood provides convenience and flexibility beyond what a traditional fume hood offers. By Gary Roepke, Senior Project Engineer, Labconco Corporation
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Silicone Molded Tubing Assemblies: A Solution For Reduced Contamination Risk And Greater Efficiency
1/13/2009
The adoption of single-use systems is one of today’s most noteworthy trends in biopharmaceutical processing. The next-generation solution, molded tubing assemblies made of silicone, can help reduce the risk of contamination in biopharmaceutical and pharmaceutical processing. By Roger Hendrick, Audrey Wipret
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White Paper: Silicone Molded Tubing Assemblies: A Solution For Reduced Contamination Risk And Greater Efficiency
1/13/2009
The adoption of single-use systems is one of today’s most noteworthy trends in biopharmaceutical processing. The next-generation solution, molded tubing assemblies made of silicone, can help reduce the risk of contamination in biopharmaceutical and pharmaceutical processing. By Roger Hendrick, Audrey Wipret
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Case Study: mAb Purification - BioSC™ Sequential Multi Column Chromatography
12/23/2008
A comparative COG’s (Cost of Goods) study for a batch and SMCC mAb capture step using Protein A media clearly demonstrates the enhanced productivity and economic savings that are achievable using BioSC by Novasep technology. A production-scale batch process might use a 1.7 meter column with a 20 cm bed height and a working capacity of 20 g/L mAb per liter of media running at 300 cm/h.
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Article: Method For Evaluating Bio-Container Transportation Applications
12/22/2008
Single-use components are finding more use in the biopharmaceutical industry. One application increasing in use is transportation of sterile liquids. There are many challenges to consider when shipping a flexible container with sterile liquids. By Charter Medical
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Expression Vector Engineering For Cell Line Development - New Roles For “Old” Sequences
11/12/2008
Expression vector and cell line engineering is the basis for expression and industrial production of biopharmaceuticals. The ultimate goal is to obtain clonal cell lines that secrete the protein of interest with high cellspecific productivity, and at consistently high levels over an extended number of cell generations, allowing for scale-up and cost-efficient large-scale manufacturing. Productivity and stability of expression are thus the prerequisites for developing commercially viable processes. By Michel Kobr, Philippe Chattelard, and Markus O. Imhof
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Performance Evaluation Of An Automated Bioreactor Sampling System For Mammalian Cell Cultivation
11/4/2008
Two common goals of biotherapeutics development are reduction in timelines and increased process understanding. An automated bioreactor sampling system developed by Groton Biosystems has proven its capacity to address those two seemingly conflicting needs for the industry. Due to the extreme length and stringent sterility requirement of mammalian cell cultivation, sampling automation of mammalian bioreactors remains an unmet need. By Groton Biosystems
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White Paper: Performance Evaluation Of An Automated Bioreactor Sampling System For Mammalian Cell Cultivation
11/4/2008
Two common goals of biotherapeutics development are reduction in timelines and increased process understanding. An automated bioreactor sampling system developed by Groton Biosystems has proven its capacity to address those two seemingly conflicting needs for the industry. Due to the extreme length and stringent sterility requirement of mammalian cell cultivation, sampling automation of mammalian bioreactors remains an unmet need. By Groton Biosystems
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Case Study: IND-Enabling Studies And Chemical Synthesis Completed — Nine Months From Lead Selection
10/1/2008
A client asked Ricerca to develop a robust chemical process, complete GLP toxicology to support a major program, and file an IND — all on a very aggressive timeline. By Ricerca Biosciences, LLC
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IND-Enabling Studies And Chemical Synthesis Completed — Nine Months From Lead Selection
10/1/2008
A client asked Ricerca to develop a robust chemical process, complete GLP toxicology to support a major program, and file an IND — all on a very aggressive timeline. By Ricerca Biosciences, LLC
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