Evaluation of single-use capsules for single-pass tangential flow filtration of mAbs and other therapeutic proteins.
Single-pass tangential flow filtration (SPTFF) has become a popular method of choice in bioprocessing for purposes of volume reduction, process intensification and continuous manufacturing. Due to its effectiveness and small footprint requirement, it can be situated between many downstream unit operations including post-harvest clarification, pre- and post- chromatography and final ultrafiltration. As the industry is looking to increase speed to market, reduce manufacturing resources and increase product safety, there has been a push to implement single-use technologies. Combining both SPTFF and single-use technology can be a powerful tool for the efficient manufacture of biologics.
In this webinar, you will learn:
- How to run SPTFF using single-use TFF devices
- How single-use devices compare to flat sheet devices in SPTFF applications
- How to scale up single-use devices for single-pass TFF applications
- Benefits of using single-use TFF in single-pass applications