Newsletter | June 25, 2021

06.25.21 -- The Rise In Single Use Containment For CMOs

Facing The Challenges: Single-Use Approaches To Powder Transfer

Media and buffer preparation is a key part of the biopharmaceutical manufacturing process, and while it doesn’t have to be carried out in sterile conditions, improving the powder transfer process makes this step cleaner, safer, and more efficient, protects personnel, and could cut time and costs as well.

Methods Of Containment For Solid-Dose Blending And Manufacturing

Dry mixing of granular and other processing constituents includes a significantly high number of blending steps. This includes potent and highly hazardous compounds, excipients, and materials such as lubricants as processing aids. This guide depicts a sampling of flexible containment applications to a variety of styles of equipment as standard and customized containment solutions.

The Rise In Single-Use Containment For CMOs

This webinar discusses flexible containment, containment performance using a case study for an oral solid dose (OSD) process, shared facilities and HBEL/ADE requirements, and benefits global CDMOs realize with flexible containment.

Single-Use Systems For Charging And Offloading Pharma Powder Transfer
While pharmaceutical and biopharmaceutical manufacturers can choose from a broad array of containment systems, not all are suited to processes where high-level containment is critical. For OEB Level 5 containment, or for processes where personnel safety and cross-contamination are key concerns, only the highest-performing containment systems make sense.
Boost Profits With Single-Use Powder Transfer In Biopharma Manufacturing

While media and buffer materials have been notorious contributors to airborne particulates and contamination in the past, they don’t have to be. Many biopharmaceutical manufacturers are implementing single-use containment and transfer of media and buffer materials to prevent feedstock contamination and promote worker safety.

Developing A Disposable Grade-A Aseptic Fill/Finish Isolation System

Isolation of aseptic processes is not a new technology. Flexible film isolation has been used in aseptic processing since the 1970s, but these systems tended to be a composite of stainless-steel chambers and airflow modules with a flexible film user interface. Learn how Solo Containment developed a fully disposable aseptic isolation system.