01.11.21 -- The AAV Vector Challenge With Selecta's Dr. Carsten Brunn

The most common storage is ultra-low temperature storage, but the fastest growing is cryogenic, in vapor-phase liquid nitrogen. This transition is huge. Chain of temperature and custody data is imperative.  

This is the first installment in a three-part series that examines the causes of protein aggregation and practical steps you can take to mitigate the risk.

Bioprocessing has been used for decades for the industrial production of beverages and for the production and preservation of food and feed ingredients. 

Powder-handling processes haven’t kept pace with advances in single-use transfer technologies. This application note posits a better way to bring powders to the hydration process for upstream manufacturing.

A new platform that includes digital technologies and data management, process analytical technologies, and intensified processing will drive next-generation bioprocessing.

Successful technology transfer is reliant on a few key variables including robust process characterization and communication and collaboration among multiple teams and sites. 

The biopharma industry has ambitions to accelerate industry 4.0. This white paper explores the major bottlenecks in the development life cycle and the current barriers to effective digital transformation.

There's a biopharma production shift from manual processes to automated intervention. This paper exemplifies the use of sensors for in-process control of upstream and downstream process parameters.

This study highlights a model system for screening optimal protein purification conditions on a mixed-mode cation exchange resin using a statistical software generated design of experiment model.

This technical bulletin highlights the results of conductivity testing to characterize recirculation mixing performance of single-use systems deployed in QuaDrum rigid outer containers (ROCs).

A single vendor offers access to a network of experts who can share knowledge about a project as it moves from phase to phase, thus helping to navigate its path toward commercial success. 

This interview with Dr. Lars Geiger, director of global projects at Evonik, reviews key trends and scale-up challenges to manufacture a substance via fermentation.

Our objective is to help speed your molecule through early-phase trials to prepare you for commercial success. This e-book explains our comprehensive support to help streamline the end-to-end process.

ISR conducted approximately two dozen pieces of research for syndication in 2019. This summary highlights learnings from these projects and provides real, usable data for 2020 activities.

This webinar focuses on the critical chemistry, manufacturing, and controls (CMC) elements of a product’s life cycle and the regulatory submissions support and strategy necessary for a successful biologics license application (BLA).