Datasheet: Single Use, Disposable, Ready To Use Pilot To Industrial Scale Cassettes- Sius™ - BD

Sius™ is the first truly single-use tangential flow filtration cassette for the biopharmaceutical industry. These single-use cassettes have been designed to offer comparable performance to reusable products at a fraction of the cost. Each cassette arrives pre-sanitized, ready to be used for processing after equilibration with buffer. Sius™ cassettes are available in a range of surface areas from 0.5 m2 to 2.5 m2. Cassettes can also be stacked together to provide greater surface areas. These cassettes have been developed using an innovative manufacturing approach that provides an efficient cassette production process that costs significantly less than comparably sized reusable products. Moreover, the cassettes are completely interchangeable with existing cassette hardware making them an ideal choice for many Tangential Flow Filtration (TFF) processes.

TFF cassettes are well established for the concentration and diafiltration of biomolecules. TFF cassettes are typically used in a process and then cleaned between uses with a Clean-In-Place (CIP) operation. This method of reuse requires a significant investment of raw materials, utilities, energy, and time. The cassette is used repeatedly until its process performance has deteriorated below acceptable limits and its productivity is reduced. Novasep now offers the first purpose-built single-use tangential flow filtration cassette for the biopharmaceutical industry.