qMod Camera To Characterize Cell Critical Quality Attributes (CQAs)

Digital dye-free camera to characterize cell Critical Quality Attributes (CQAs)

Ovizio’s qMod quantitative phase imaging camera can convert a regular brightfield microscope into a versatile 3D quantitative imaging platform for biological applications. It can be fixed onto the C-mount where a camera is usually attached to the microscope. The qMod is a convenient and fast solution to characterize the cell Critical Quality Attributes (CQAs) in transparent supports: petri dishes, flasks and
multi-well plates.

Designed for high precision, the qMod generates real-time holographic fingerprints of cell culture, enabling the user to select and observe cells individually based on a pre-defined set of parameters. Using the OsOne software, scientists can count objects, distinguish between living and dead cells, track morphological changes, and monitor the aggregation rate. To offer the best possible resolution every time, images acquired with the OsOne software can be refocused post acquisition.

This unique approach opens the door to even more applications, with the possibility of confirming results in a dye-free set-up, avoiding sample preparation, reagents and cell fixation, and thereby also eliminating the need to use potentially toxic and often expensive reagents.