Product/Service

p-Aminobenzamidine Agarose 6XL Affinity Adsorbent

Source: Astrea Bioseparations
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p-Aminobenzamidine Agarose 6XL is an affinity adsorbent for purification of serine proteases and esterases such as trypsin, thrombin, kallikrein, urokinase, acetyl cholinesterase and alkaline phosphatase.

p-Aminobenzamidine Agarose 6XL can be used in the separation of closely related proteases, for example, trypsin from chymotrypsin, or in the removal of trace protease contamination from a final product.

Key Features

  • Affinity purification for removal of serine proteases
  • High purity p-aminobenzamidine ligand
  • Ligand binds selectively to the active site of serine proteases
  • High dynamic binding capacity
  • Highly reproducible batch to batch
  • Sanitisable with 20% ethanol/1.0 M acetic acid or 8 M urea allowing multiple cycles (not stable in NaOH)
  • Supported with a comprehensive Regulatory Support File
  • Multiple end users in regulated biopharmaceutical development and manufacturing scale processes