New Brunswick S41i CO2 Incubator Shaker

Source: Eppendorf, Inc


For over two decades New Brunswick CO2 incubators have provided researchers with a reliable, easy-to-use system for culturing cells. The New Brunswick S41i CO2 incubator shaker continues this tradition with state-of-the-art features and reliable high performance.

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The S41i is the only CO2 incubator with a built-in New Brunswick shaker, making it ideally suited for suspension cell culture applications. It combines precise temperature and CO2 control, high-temperature disinfection and a premium New Brunswick shaker for a stable and secure environment that achieves high cell yield and viability. The New Brunswick S41i also minimizes CO2 consumption without compromising cell growth and viability. Performance tests have shown that it reduces costly gas consumption when compared to competitor models.

Heavy-duty, triple eccentric drive shaker provides stable, uniform and vibration-free motion that is perfect for suspension cell culture applications.

The perfect CO2 incubation environment

Like all New Brunswick CO2 incubators, the S41i features a six-sided direct-heating profile. Gentle convection circulation of the chamber atmosphere maintains stable temperatures and CO2 control throughout the chamber. Unlike traditional forced-air culture systems, this design protects against wide fluctuations in temperature and CO2 that stress cells. No fan is required, which eliminates a classic source of contamination, disturbing vibrations, and costly HEPA filters. Direct-heating technology combined with the following additional features provide the perfect CO2 incubation environment.

  • IR sensor: Provides specific measurement and accurate control of CO2 levels, unlike traditional TC sensors that are sensitive to chamber humidity and temperature fluctuations
  • Advanced PI control: Maintains temperature accuracy and uniformity while minimizing costly gas consumption
  • Tightly sealed inner glass door: Samples can be viewed during cell culturing without compromising the sample or environment. Since the chamber remains closed when samples are viewed, temperature uniformity is maintained and costly CO2 and N2 consumption is reduced.
  • Unique perforated shelves help to ensure rapid recovery of temperature, CO2 and RH when the door is opened and closed

Designed with sample safety in mind

New Brunswick S41i is designed to keep samples free of contamination with the following features:

  • Easy-to-clean incubator chamber: Deep-drawn chamber with rounded corners and a smooth, seamless  surface eliminates a common source  of contamination and is easy to clean
  • High Temperature Disinfection (HTD) heats the internal chamber to 120 °C and holds it for 4 hours to effectively eliminate contaminants
  • Removable humidity pan and shelves slide out for fast, easy and effective cleaning. Shelves can also be easily repositioned

Intuitive touchscreen controller

Advanced and intuitive touch screen control provides a clear and accurate view of incubator conditions and allows users to track performance over time.

  • Quick viewing of multiple parameters
  • Comprehensive and rapid analysis of real time and historical conditions, including trend graphs
  • Quick changes in environmental and alarm settings, on-screen troubleshooting and diagnostics
  • 72-hour continuous data logging records environmental conditions, temperature, alarms and more
  • Password protected settings and alarm setpoints

Additional standard features include:

  • NEW Building Management System (BMS) Relay for integration into centralized building alarm system is now a standard feature
  • Programmable auto-zero port with hydrophobic filter ensures accurate CO2 calibration measurements; exceptional filtration rate of 99.99% prevents particulates from entering the sensor or chamber
  • Includes 2 shelving racks and 1 perforated shelf; fits one additional shelf (optional)
  • 25mm access port for adding instrumentation or probes
  • High quality door gasket maintains a leak-free seal
  • Ethernet port for communication and external instrument logging
  • In-line filters for gas supply inlets ensure sterility
  • Can be used under bench, on floor stand and is stackable x2 (optional stacking frame needed)

Backed by trusted service from Eppendorf

The New Brunswick S41i incubator shaker is supported by world-class Eppendorf service and support. Three service maintenance plans are offered to ensure that the CO2 incubator is maintained in proper working condition and cell culture environment is consistently stable. Certification services are also available to satisfy quality management requirements, including Installation Qualification (IQ) and Operational Qualification (OQ) certification that guarantee instrument installation and performance according to manufacturer’s specifications. Documentation is provided for regulatory compliance.


Temperature range

Ambient + 4  to 50 °C

Temperature uniformity

± 0.3 °C

Temperature control

± 0.1 °C

Temp. stability at 37 °C

± 0.1 °C

CO2 range

0.2 - 20 %

CO2 uniformity

± 0.1 %

CO2 control

± 0.1 %

CO2 stability at 5 % CO2

± 0.2 %


170 L

Internal dimensions

69.3 x 45.1 x 54 cm

External dimensions

84.8 x 83.4 x 73 cm

Net weight

152 kg

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