Newsletter | October 1, 2021

10.01.21 -- Industrializing Cell Therapy Processing

Integrated Pluripotent Aggregate Processing

Pluripotent stem cells (PSCs) and induced pluripotent stem cells (iPSCs) are promising sources for the next wave of cell therapies and regenerative medicine. In this application note we demonstrate a closed and automated solution to gently process PSC aggregates that does not adversely impact cell viability, morphology, function, or efficacy.

Expanded T Cell Harvest With An Acoustic Cell Processing System

In this application note, you will learn how an automated system using acoustic technology enables user-friendly automation of the harvest, wash, and concentrate steps required to prepare T cells for preservation.

Cell Therapy Manufacturing: DMSO Removal For Thawed Apheresis Material

For CAR-T processes that require a freezing step between apheresis collection and manufacturing, it is critical upon thaw to remove dimethyl sulfoxide (DMSO), a standard component of cryoprotectants, from the product to ensure the utmost cellular health of the apheresis material. In this application note, you will learn how a closed, integrated manufacturing platform can gently process cells, supporting the removal of DMSO and cell debris.

Freedom To Optimize With An Acoustic Cell Processing System

Advancing cell and gene therapies from research to commercial manufacturing requires innovative technologies that can produce high-quality product while ensuring efficient, easy-to-use, and cost-effective processing. In this webinar, you will learn more about the latest innovations in cell therapy manufacturing leveraging acoustic soundwave technology to gently and efficiently process cells.

Accelerating Cell Therapy Manufacturing Through Robust Process Development

In this webinar, you will learn process development strategies for solutions that can be seamlessly translated and implemented for use in commercial production. Topics include an introduction to a fit-for-purpose cell therapy manufacturing solution, process development case studies that support a variety of unit operation steps across cell types, and wash and concentration of T cells and aggregate processing of induced pluripotent cells.