How Do Bioreactors Boost Reproducibility?

Whether repeating experiments for publication or producing compounds in an industrial lab, reproducibility is key. Differences in cultures from batch to batch often arise due to variability in flask size, flask geometry, shake speed, and shake orbit.¹ Therefore, combining cells or products from individual small cultures should be avoided when uniformity is essential.

Bioreactors are not merely inert vessels for cell growth; they closely monitor and dynamically adjust biological and mechanical process conditions automatically. Options for vessel size, control sensors, and pumps in modern bioreactors make them ideal growth containers for a variety of cell types. Controlling reaction environments using software enables better control and data collection throughout the growth phase.