Case Study

How Boehringer Ingelheim Significantly Ease Seamless Process Transfers

Source: Sartorius Stedim Biotech

Conceptual Design for Single-Use Downstream Process

The early involvement of Integrated Solutions bioprocess consultants, facilitated the implementation of a global single-use platform within Boehringer Ingelheim’s manufacturing network

Implementation of Multifunctional FlexActs

The equipment selected (FlexAct® Single-Use systems) provides a flexible solution to cell culture manufacturing needs for buffer preparation, low pH virus inactivation, virus removal and ultrafiltration | diafiltration operations. Those systems could be perfectly integrated into a fully Single-Use and functionally closed platform due to a high degree of standardization.

Enabling global single-use Platform for Boehringer Ingelheim

“The ability to work across different sites at a global scale with one Boehringer Ingelheim Project team and one Sartorius project team, truly enabled the success of the project.” Jan Feuser – Head of Clinical Supply Facility Head of Clinical Supply Facility, Downstream

The implementation of a common DCU control unit

Makes operators familiar with FlexAct® Single-Use systems and minimizes training requirements. The system automation reduces operator involvement (LEAN).