Case Study: Hepatic Fat Accumulation In Hyperlipidemic Patients As Measured By Magnetic Resonance Spectroscopy And Magnetic Resonance Imaging

When used in combination, magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) can offer unique advantages in the study of hepatic fat in hyperlipidemic patients. MRI assesses differences in local environments to produce high contrast images, while MRS is capable of displaying minute differences in the magnetic properties of different chemical compounds to provide a unique biochemical signature. As a result, MRS can quantify important information on cellular activity and metabolism within the imaged region.

Because of its unique capabilities in employing novel imaging technologies in drug development trials, American College of Radiology (ACR) Image Metrix was chosen for a groundbreaking, randomized clinical trial testing the efficacy and safety of an MTP inhibitor.