Application Note

Ensuring Compliance: Validation Of Virus Filtration

Source: MilliporeSigma
Ensuring Compliance: Validation Of Virus Filtration

Virus safety is a critical consideration in the manufacture of biological therapeutics. The concern over virus contamination is related to viruses endogenous to the manufacturing cell line as well as adventitious viruses that can be introduced during manufacturing.There are specific considerations for all virus filtration clearance studies and understanding these before initiation of the study will help assure a successful outcome where the results meet the targets.