Application Note

Characterization And Engineering Performance Of The Allegro™ STR 200 Single-Use Stirred Tank Bioreactor System

Source: Pall Biotech
Pall: provider of filtration, purification and separation technologies

Currently, stirred tank reactors (STRs) represent the gold standard for the large scale growth of suspension cell lines. Cell culture performance is strongly influenced by the efficiency of mixing, as measured by the oxygen mass transfer coefficient (kLa O2) and mixing time. The success of traditional stainless steel or glass STR systems lies in their impeller driven agitation that efficiently mixes large volumes of culture fluid.