BIOSTAT® A - Professional Entry-Level Solution For Cell Culture And Microbial Fermentation
With its new BIOSTAT A, Sartorius Stedim Biotech presents a compact bioreactor | fermenter designed specifically as an entry-level model for fermentation and cell culture as well as for educational purposes.
WHITE PAPERS & CASE STUDIES
Scale-Up Of Microbial Fermentation Using Recombinant E. Coli
Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/ sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures.
High Density Hybridoma Cell Culture In A Packed-Bed Bioreactor
Packed-bed bioreactor cell culture is generally accepted as one of the best methods to simulate the conditions of animal cell growth in vivo since cells are maintained in a low-shear environment with constant refreshment of nutrients and removal of waste. By Ray Rose, Stacey Willard, and Ma Sha
Anaerobic Yeast Fermentation Using Redox Control
Metabolic activity of microorganisms depends on many factors, including oxidation and reduction reactions, or the “redox potential” of the culture environment.
Rip It Up And Start Again: Developing A Bioreactor For Vaccines
While incremental advances can create solutions to technological problems, sometimes the only way to achieve the required result is to rip up the old rulebook and start from scratch. That’s the approach ATMI LifeSciences took in developing a bioreactor for vaccine manufacture. By Jose Castillo, Director of Cell Culture Technologies at ATMI LifeSciences
Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities
CEVEC has established a master cell bank (MCB) of CAP cells growing in suspension, tested and certified according to ICH guidelines and European Pharmacopeia. Simple and reliable protocols allow for the fast generation of customized producer cell lines for pharmaceutically relevant proteins based on the parental permanent CAP cells under controlled and optimized conditions.
Process For Scale-Up Of Adherent Vero Cells From Static Cell Factories To Influenza Production
In cell culture-based vaccine production, scale-up of adherent cells is challenging. This study shows a process for scaling up adherent Vero cells from static cell factories to influenza production at 50 L scale using WAVE Bioreactor™ systems and ReadyToProcess single-use equipment.