bio-small-scale-bioreactors-995x60 bio-small-scale-bioreactors-995x60

WHITE PAPERS & CASE STUDIES

  • Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities
    Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities

    CEVEC has established a master cell bank (MCB) of CAP cells growing in suspension, tested and certified according to ICH guidelines and European Pharmacopeia. Simple and reliable protocols allow for the fast generation of customized producer cell lines for pharmaceutically relevant proteins based on the parental permanent CAP cells under controlled and optimized conditions.

  • Process For Scale-Up Of Adherent Vero Cells From Static Cell Factories To Influenza Production

    In cell culture-based vaccine production, scale-up of adherent cells is challenging. This study shows a process for scaling up adherent Vero cells from static cell factories to influenza production at 50 L scale using WAVE Bioreactor™ systems and ReadyToProcess single-use equipment.

  • Crucial Factors In Choosing Bioreactors

    Advanced benchtop bioreactors can harmonise unit operations between development and production while supporting the aims of quality by design. By Kathrin Schmale, Strategic Marketing Manager, DASGIP & Karl Rix, CEO, DASGIP BioTools, LLC

  • Scale-Up Of Microbial Fermentation Using Recombinant E. Coli
    Scale-Up Of Microbial Fermentation Using Recombinant E. Coli

    Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/ sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures.

  • Amino Acid Fermentation: Evaluation Of Scale-Down Capabilities

    Rising cost and time pressures in bioprocess development together with rapidly evolving regulatory requirements make process development efforts a special challenge these days.

  • Filter Integrity Testing Troubleshooting Guidelines
    Filter Integrity Testing Troubleshooting Guidelines

    Integrity Testing is a non-destructive physical test to determine the presence of over-sized pores or other defects that may compromise a given filter’s retention capability. By Wayne Garafola, Sartorius Stedim North America, Inc.

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PRODUCTS & SERVICES

HyPerforma™ Single-Use Fermentor (S.U.F.) HyPerforma™ Single-Use Fermentor (S.U.F.)

The S.U.F. is engineered for optimal oxygen mass transfer, mixing, and temperature control, and performs comparably to traditional stainless steel systems. Using traditional, fundamental engineering principles, scale-up and process development work is streamlined – offering you cost savings and efficiency. 
 

Sartocheck® 4 Plus Bag Integrity Tester Sartocheck® 4 Plus Bag Integrity Tester

Sartorius introduced the very first Sartocheck® filter integrity tester in 1980. Over the 30-year period of continual enhancement that followed, the Sartocheck® product line evolved into the most sophisticated automated integrity test solution and the preferred choice of critical customers who insist on the best in performance and quality.

DASbox - Mini Bioreactor System DASbox - Mini Bioreactor System

The DASbox is a very compact fully featured Parallel Bioreactor System. Featuring miniature bioreactors for working volumes from 60mL to 250mL DASbox is perfectly suited for design of experiment (DoE) applications in cell culture as well as microbial process development.

Peptides Synthesis Peptides Synthesis
Lonza provides customers with a tailored approach built around a unique peptide competency that helps your product reach its full potential.
Chemical Synthesis:  Small Molecule API Manufacturing Chemical Synthesis: Small Molecule API Manufacturing
Chemical synthesis for small molecule manufacturing is one of Lonza's key competencies.
Sartofluor® GA 0.2 µm & 0.1 µm Sterilizing Filter Cartridge Sartofluor® GA 0.2 µm & 0.1 µm Sterilizing Filter Cartridge
Sartofluor GA filter cartridges, are specially designed for sterile venting and gas applications.
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