BIOSTAT® A - Professional Entry-Level Solution For Cell Culture And Microbial Fermentation
With its new BIOSTAT A, Sartorius Stedim Biotech presents a compact bioreactor | fermenter designed specifically as an entry-level model for fermentation and cell culture as well as for educational purposes.
WHITE PAPERS & CASE STUDIES
Scale-Up Of Microbial Fermentation Using Recombinant E. Coli
Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/ sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures.
Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities
CEVEC has established a master cell bank (MCB) of CAP cells growing in suspension, tested and certified according to ICH guidelines and European Pharmacopeia. Simple and reliable protocols allow for the fast generation of customized producer cell lines for pharmaceutically relevant proteins based on the parental permanent CAP cells under controlled and optimized conditions.
Process For Scale-Up Of Adherent Vero Cells From Static Cell Factories To Influenza Production
In cell culture-based vaccine production, scale-up of adherent cells is challenging. This study shows a process for scaling up adherent Vero cells from static cell factories to influenza production at 50 L scale using WAVE Bioreactor™ systems and ReadyToProcess single-use equipment.
HarvestClear™ Filtration System For Harvest Of Small-Scale Bioreactors
The clarification of batch and fed-batch bioreactor systems can pose a practical challenge to biopharmaceutical manufacturers due to high cell densities.
Crucial Factors In Choosing Bioreactors
Advanced benchtop bioreactors can harmonise unit operations between development and production while supporting the aims of quality by design. By Kathrin Schmale, Strategic Marketing Manager, DASGIP & Karl Rix, CEO, DASGIP BioTools, LLC
Amino Acid Fermentation: Evaluation Of Scale-Down Capabilities
Rising cost and time pressures in bioprocess development together with rapidly evolving regulatory requirements make process development efforts a special challenge these days.