bio-small-scale-bioreactors-995x60 bio-small-scale-bioreactors-995x60

WHITE PAPERS & CASE STUDIES

  • High Density Hybridoma Cell Culture In A Packed-Bed Bioreactor
    High Density Hybridoma Cell Culture In A Packed-Bed Bioreactor

    Packed-bed bioreactor cell culture is generally accepted as one of the best methods to simulate the conditions of animal cell growth in vivo since cells are maintained in a low-shear environment with constant refreshment of nutrients and removal of waste. By Ray Rose, Stacey Willard, and Ma Sha

  • Anaerobic Yeast Fermentation Using Redox Control
    Anaerobic Yeast Fermentation Using Redox Control

    Metabolic activity of microorganisms depends on many factors, including oxidation and reduction reactions, or the “redox potential” of the culture environment.

  • Rip It Up And Start Again: Developing A Bioreactor For Vaccines

    While incremental advances can create solutions to technological problems, sometimes the only way to achieve the required result is to rip up the old rulebook and start from scratch. That’s the approach ATMI LifeSciences took in developing a bioreactor for vaccine manufacture.  By Jose Castillo, Director of Cell Culture Technologies at ATMI LifeSciences

  • Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities
    Cultivation Of Human CAP Cells: Evaluation Of Scale-Down Capabilities

    CEVEC has established a master cell bank (MCB) of CAP cells growing in suspension, tested and certified according to ICH guidelines and European Pharmacopeia. Simple and reliable protocols allow for the fast generation of customized producer cell lines for pharmaceutically relevant proteins based on the parental permanent CAP cells under controlled and optimized conditions.

  • Process For Scale-Up Of Adherent Vero Cells From Static Cell Factories To Influenza Production

    In cell culture-based vaccine production, scale-up of adherent cells is challenging. This study shows a process for scaling up adherent Vero cells from static cell factories to influenza production at 50 L scale using WAVE Bioreactor™ systems and ReadyToProcess single-use equipment.

  • A Comparison Of Performance Using Three Bioreactor Systems
    A Comparison Of Performance Using Three Bioreactor Systems

    Eppendorf has introduced a new benchtop cell culture bioreactor that combines the benefits of single-use technology with the trusted performance and true scalability of a stirred-tank design. CelliGen™ BLU eliminates the need for autoclaving and cleaning, reduces validation requirements, provides rapid turn-around between runs, minimizes startup costs, and significantly reduces the risk of contamination because the culture vessel is only used once and then discarded.

More White Papers & Case Studies

PRODUCTS & SERVICES

Sartocheck® 4 Plus Bag Integrity Tester

Sartocheck® 4 Plus Bag Integrity Tester

Sartorius introduced the very first Sartocheck® filter integrity tester in 1980. Over the 30-year period of continual enhancement that followed, the Sartocheck® product line evolved into the most sophisticated automated integrity test solution and the preferred choice of critical customers who insist on the best in performance and quality.

SciLog Automated Bioprocessing Systems

SciLog Automated Bioprocessing Systems

Parker domnick hunter bioprocessing filtration solutions are available as part of an integrated single-use system reducing capital costs, footprint and validation of cleaning regimes. Our products are aimed to minimize the potential risk and maintain flexibility as product development moves from R&D to full commercial production. We integrate currently validated components into a fully validated and ready-to-use system solution.

Intelligent Laboratory Metering Systems

Intelligent Laboratory Metering Systems

Parker dominck supplies a variety of laboratory equipment. Optimize filtration parameters and maximize filter throughput with automated laboratory scales for NFF (normal flow filtration) and TFF (tangential flow filtration). For precise metering Parker domnick’s metering systems provides applications specifically for chemical and biological applications.

Optimize Filtration Processing, Maximize Filter Life - SciFlex™ NFF

Optimize Filtration Processing, Maximize Filter Life - SciFlex™ NFF

The SciFlex™ NFF automated single-use normal flow filtration (NFF) system automatically monitors, adjusts and documents pressures and flow rate to optimize processing times, maximize filter life and efficiency.

Automated Tangential Flow Filtration System - SciFlex™ TFF

Automated Tangential Flow Filtration System - SciFlex™ TFF

The Scilog SciFlex™ TFF is a automated Tangential Flow Filtration System.

Integrated Processing Filtration Solution

Integrated Processing Filtration Solution

The HarvestClear™ Filtration System is a complete solution for cell culture harvest that provides fast, automated clarification of bioreactor outputs up to 20L.

Hardware

Hardware

Biopharma manufacturing processes are comprised of a series of operations — from mixing, chromatography, to liquid transport. Pall provides hardware and workstations to optimize each operation, as well as consultancy services to provide solutions, validation, and technical support to help manage your procedures.

Instruments

Instruments

Pall offers integrity testing instrumentation, single-use systems, bioprocessing workstations, for upstream and downstream applications.  To help optimize your processes, Pall offers validation, process solutions, and technical support for single-use systems.

More Products & Services
Newsletter Signup
Newsletter Signup
By clicking Sign Me Up, you agree to our Terms and that you have read our Privacy Policy.