Agilent Technologies Demonstrates New Generation Of Ion Mobility Technology To Enhance High-Resolution Mass Spectrometry Capabilities
Agilent Technologies Inc. Recently introduced analytical research findings using new ion mobility technology combined with a modified high-resolution iFunnel Quadrupole-Time-of-Fight LC/MS system.
WHITE PAPERS & CASE STUDIES
Better Characterization of Biomolecules Using Agilent AdvanceBio Reversed-Phase Columns
Reversed-phase (RP) is one of the three key techniques used in biochromatography and is particularly valuable because of its compatibility with LC/MS detection. And small particle improvements, such as those found in Agilent ZORBAX RRHD 300A, 1.8 um columns, make RP an attractive choice for many biopharmaceutical applications.
Measuring Viability Decline In Animal Cell Suspension Cultures With A Spectrophotometer
Thermo Scientific™ NanoDrop™ spectrophotometers are the gold standard for the quantification and analysis of nucleic acids and proteins; however, there are a variety of other applications to which they are well suited. By Patrik O. Michel, Ph.D., Christophe Degen, Mélanie Hubert, Lucia Baldi, Ph.D., David L. Hacker, Ph.D., and Florian M. Wurm, Ph.D
An In Vitro Microplate Assay That Can Monitor IL-6 Secretions From SKOV-3 Ovarian Carcinoma Cells
Epidermal growth factor receptor (EGFR) is expressed in up to 70% of epithelial ovarian cancers (EOCs). By Brad Larson and Peter Banks, BioTek Instruments, Inc., Nicolas Pierre, CisBio US Inc., and Stephanie Georgiou, Enzo Life Sciences
Micro-Volume Determination Of Labeling Efficiency In A Standard Microplate Reader
A variety of methods and reagents have been developed to efficiently label biomolecules. By Peter J. Brescia, Applications Scientist, BioTek Instruments, Inc.
Quantitative Determination Of Bisphosphonate Pharmaceuticals And Excipients By Capillary IC-MS
Bisphosphonates are a group of compounds that are used as active pharmaceutical ingredients (APIs) to treat bone disorders including osteoporosis, Paget’s disease, and hypercalcemia. Typical methods for bisphosphonates analysis include liquid chromatography (LC) with derivatization and/or ion pairing, ion chromatography (IC), capillary electrophoresis (CE), and gas chromatography (GC) with derivatization. By Leo Jinyuan Wang and William C. Schnute, Thermo Fisher Scientific
Laser Induced Breakdown Spectroscopy (LIBS): Application Note
Using a pulsed laser to create a surface ablation on a sample and then spectroscopically analyzing its elemental and molecular composition is known as Laser Induced Breakdown Spectroscopy (LIBS). This form of spectroscopy has been greatly helped with the advent of fiber optic spectrometers, as their flexibility has enabled the measurement of LIBS plasma in harsh or challenging environments. This application discussed the advantages of LIBS, and also explores different instruments that can be used in such an application.