Insights On Downstream Manufacturing
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Be A Gain Changer, 2x Throughput, Only With Supor Prime
5/4/2024
Highly concentrated antibody drugs hold promise in revolutionizing patient treatment. However, new treatments bring forth new challenges in manufacturing. Engineered to deliver the high throughput capacity of high-value drug products, Cytiva Supor™ Prime filters minimize product loss and waste, guaranteeing optimal yield. Watch to learn more about these innovative filters.
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Risk Control | Bulk Filling Application
4/25/2024
Learn about a bulk filling system that enables you to achieve risk control, accuracy, and superior product recovery in your fill and finish operations.
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AAV Titer Estimation With Mass Photometry
4/25/2024
How do new mass photometers, featuring a new titer estimation tool, perform as a powerful analysis technique when used to evaluate the quality of AAV samples.
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AAV Analytics: Key Considerations When Developing A Clinical Program
4/25/2024
Finding partners with the necessary skills to optimize AAV processes is crucial for minimizing risk. Explore key considerations for advancing your therapy from concept to commercialization.
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Bulk Filling Of Drug Substance | Accurate Aliquoting
4/24/2024
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Streamlining Single-Use Assemblies In The Bulk-Fill Step Of Downstream Processing
4/24/2024
Single-use (SU) systems and components are growing in demand as they offer minimal contamination risk. Review a standardized SU assembly for bulk-fill processing that aims to improve efficiency.
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New Instrumentation Expands Sediment Velocity AUC’s Utility
4/24/2024
Purified adeno-associated viruses (AAVs) are prepared as a variety capsid species that must be characterized and quantified to ensure safety and efficacy.
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Identify And Quantify AAV Fill States Using Analytical Centrifugation
4/24/2024
Purified AAVs are prepared as a variety capsid species. To ensure gene therapy safety and efficacy, it is crucial to characterize and quantify those species.
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De-Risking The Aseptic Drug-Filling Process And Optimizing Production
4/17/2024
Aseptic drug-filling poses significant risks for manufacturers that can increase costs and timelines. Leveraging proven expertise and efficiency can ensure the production of safe, efficacious products.
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Robust Development Of Downstream Process Technologies For AAV
4/17/2024
The focus of this study was to optimize the three primary downstream processing steps for AAV particle purification utilizing a design of experiments (DoE) methodology and screening devices.