1. Complex Surfactant Purification Using Advanced Dual Detection Preparative LC

    Polysorbate 80 or Tween® 80 (TW80) is a nonionic surfactant and emulsifier often used in foods and cosmetics. 

  2. Peptide Purification Using An Advanced Flash And Preparative LC System

    Solid phase peptide synthesis (SPPS) is one of the most commonly used approaches for synthesizing peptides used in research, clinical, and commercial applications.

  3. Balancing The Need For Complete Characterization Of Protein-Protein Interactions

    Protein formulation is becoming increasingly complex due to the complexity of the biomolecules to be formulated and regulatory necessities in the process.  Drug product development researchers need reliable data on how the formulation of their biologics can impact potential aggregation, physical/chemical instability, and viscosity issues before proceeding too far down the development road. This paper looks at both Kd and B22 as predictors of formulation success, and potential drawbacks of each."

  4. Single-Use Standardization: Is It Holding Back The Biopharma Industry?

    The data from BioPlan Associates’ 12th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production speaks to the industry’s ongoing desires for standardization in single-use devices. As usage of these disposable devices increases, the gap between the importance of standardization and end-users’ satisfaction with their supplier’s standardization efforts has steadily been worsening. 

  5. Endotoxin Removal From Bench To Process Scale

    Endotoxin or lipopolysaccharides (LPS) are highly toxic components of the cell wall of Gram-negative bacteria and are often present in significant amounts in bacterial cell expression systems such as E.coli.

  6. Prioritizing The BioPharma Portfolio – Get The Right Assets On The Bus (and The Wrong Ones Off)

    Everyone is looking for the silver bullet: the product that will change the face of biopharmaceuticals and draw blockbuster revenues. If you have one of these, you can stop reading. But if you are like most companies, your portfolio is a mix of some winners, some underachievers, and a lot of “in-betweeners.” The process of getting the right assets on the bus (and funded) in a cash-strapped environment is as much an art as a science. As consultants to the industry for many years, we’ve seen myriad processes – both good and bad. 

  7. Microbiome Research: The New Horizon In Therapeutic Value Creation

    There are many potential causes of microbial imbalance (dysbiosis) in adulthood, including repeated and inappropriate exposure to antibiotics in earlier years, alcohol misuse, or an inappropriate diet.  Balancing the intestinal microbiome is a logical approach to preventing or reversing diseases caused by dysbiosis. 

  8. sCMOS Cameras for OEM

    These new OEM cameras from Hamamatsu feature an advanced scientific CMOS (sCMOS) image sensor capable of high resolution, fast frame rates, and low noise simultaneously. With their small size, board-level design, and simple, low-cost integration, these OEM cameras are ideal for imaging in life science, failure analysis, and semiconductor inspection.

  9. Scientific Board-Level sCMOS Camera: C11440-50B

    This datasheet includes a detailed description of the C11440-50B sCMOS board level camera, as well as information on its features, functions, and specifications. This camera is ideal for ratio imaging, FRET, TIRF microscopy, time lapse fluorescence imaging, real-time confocal microscopy, failure analysis, and semiconductor inspection applications.

  10. Scientific Board-Level sCMOS OEM Camera: C11440-52U

    This digital sCMOS board level camera features 4.0 megapixel resolution, a frame rate of 30 frames/s at 2048 x 2048 resolution, over 70% quantum efficiency (at peak), and 2.3 electron camera noise

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