1. Why Will We Always Need New Antibiotics? Rethinking The Bacteria Fight

    Antibiotics made modern medicine possible. Before the introduction of antibiotics, suchas penicillin in the 1940s, infectious diseases as simple as common skin infections claimed countless victims. In the early 1900s, 90% of children with bacterial meningitis died.

  2. Optimizing Methods In Microtissue Cultivation

    Cells grown in standard suspension or monolayer culture lose many features that are characteristic of cells in tissues and limit their use to study certain aspects of cell biology.

  3. Kinetic Ligand Binding And 3D Tumor Invasion Technologies To Assess Drug Residence Time And Anti-metastatic Effects

    Metastasis, the spread of cancer cells from the original tumor to secondary locations within the body, is linked to approximately 90% of cancer deaths. The expression of chemokine receptors, such as CXCR4 and CCR7, is tightly correlated with the metastatic properties of breast cancer cells. In vivo, neutralizing the interaction of CXCR4 and its known ligand, SDF1-α (CXCL12), significantly impaired the metastasis of breast cancer cells and cell migration.

  4. Staying On Top Of Microbes: Smarter Testing Technology For Labs Of The Future

    Over the past decade, drug and medical device manufacturers have become leaner and more stream-lined. Given the current market pressures, companies are looking for more ways to improve their bottom-line.

  5. World’s Leading Proofreading Verification And Document Inspection Solution Demo

    We invite you to attend one of our exclusive webinars introducing you to DocuProof the world’s leading proofreading tool for text verification, document inspection and document comparison.

  6. Label-Free Phenotype MicroArrays™ Analysis Of Cellular Energetics And Apoptotic Activity Using Microplate Reading And Phase Contrast Imaging

    Phenotypic screening, or the determination of the effects (phenotypes) that a molecule has on a cell, tissue, or whole organism, dates back to earliest drug discovery efforts.

  7. Quantification Of MMP Activity And Inhibition In A 3D Tumor Invasion Model

    Metastasis, the spread of cancer cells from the primary tumor to secondary locations within the body, is linked to approximately 90% of cancer deaths1. Penetration through the basement membrane is a critical step during the metastatic process, and has been linked to the formation of membrane superstructures called invadopodia2.

  8. World Courier Biomedical Seminar 2015

    The World Courier Biomedical Seminar is the global conference where pharmaceutical, research and regulatory leaders receive insight on the dynamic industry — and the impact on global specialty transport. You’ll collaborate with industry thought leaders to surface new and innovative ways to solve business challenges.

  9. Study Of The imPULSE Single-Use Mixing Systems Performance

    The purpose of this mixing study is to characterize the performance of ASI’s imPULSE Single-Use Mixing System in a range of sizes and solution viscosity. Conductivity, pH and optical density, where applicable, were monitored to indicate the time required to achieve a uniform solution. In addition, the heat transfer capability of jacketed systems was also evaluated by recording the temperature at various points over time while mixing.

  10. imPULSE Mixing Study Summary Using Computational Fluid Dynamics (CFD)

    The purpose of the Computational Fluid Dynamics (CFD) Study was to predict the mixing performance of ASI’s imPULSE Single-Use Mixing System across a range of small, medium and large scale vessels and fluid viscosities.

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