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  1. 10 Critical Components Of A Successful Global Drug Development Plan
    9/30/2016

    We use plans every day to help us arrive at our desired destinations.  Pilots utilize flight plans prior to take off — although they have flown to their destination perhaps hundreds of times before, they nevertheless reviews and follows a flight plan. Likewise, ship’s captains also file plans and chart courses. Road maps provide guidance on how to drive from point A to point B, though today most people rely on electronic global positioning systems (GPS) to assist with navigation.

  2. How CHT Ceramic Hydroxyapatite Works
    9/30/2016

    CHT ceramic hydroxyapatite is a versatile chromatography support used for separation of biological molecules as diverse as polyclonal and monoclonal antibodies, antibody fragments, enzymes, nucleic acids, and membrane proteins. The interactions that occur between CHT and the molecules it binds are complex; this article aims to clarify the most significant features of these interactions.

  3. How CHT Ceramic Hydroxyapatite Works Application Note
    9/30/2016

    CHT ceramic hydroxyapatite is a versatile chromatography support used for separation of biological molecules as diverse as polyclonal and monoclonal antibodies, antibody fragments, enzymes, nucleic acids, and membrane proteins. By Paul Ng, Jie He, and Andrew Cohen, Bio-Rad Laboratories, Inc., Hercules, CA 94547

  4. Process Development and Scale-Up of Ceramic Hydroxyapatite Application Guide
    9/29/2016

    This is a guide for the use of CHT as a media support in your purification process.

  5. Process Development And Scale-Up Of Ceramic Hydroxyapatite
    9/29/2016

    CHT is a leading purification medium of biomolecules in today’s demanding downstream process industry. Its mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous with other chromatographic methods. The diverse binding capabilities of CHT for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

  6. Stain Free Gels Confirm Protein Purity Brochure
    9/29/2016

    A proven method for confirming protein purity and yield without the need for gel staining steps. Stain-free gels provide visual confirmation of protein purity and yield by gel electrophoresis in less than 30 minutes. Stain-free technology is perfect for drug discovery, drug development, and method development for preclinical research.

  7. Stain Free Gels Confirm Protein Purity
    9/29/2016

    A proven method for confirming protein purity and yield without the need for gel staining steps. Stain-free gels provide visual confirmation of protein purity and yield by gel electrophoresis in less than 30 minutes. Stain-free technology is perfect for drug discovery, drug development, and method development for preclinical research.

  8. Biomanufacturers: How To Reduce The Complexity Of Custom Single-Use Assemblies
    9/28/2016

    Based on a discussion with Guy Matthews, market development manager with Parker dominick hunter.

  9. Modeling Time-Dependent Processes More Accurately To Improve Quality And Control
    9/28/2016

    Batch processes are common in pharmaceutical, biopharmaceutical, food, beverage and chemical industries. When building models across various batches one may often encounter varying batch lengths and the batches may start from various relative points of time in a chemical context. Batch Modeling is important for process development and understanding the process for batch similarity and why some batches give a product quality outside the specifications.

  10. Best Practices For Measuring System Quality For Drug-Device Combination Products
    9/28/2016

    Combination product development is a complex matter governed by different areas of regulatory oversight. In my previous article, we discussed which current good manufacturing practice (cGMP) requirements apply when drugs, devices, and biological products are combined, and the typical pitfalls to avoid when doing so.