Downloads

  1. Cultivation Of CHO Suspension Cells And SEAP Expression In The Wave-Mixed Single-Use Finesse SmartRocker Bioreactor
    3/31/2015

    This application note describes the cultivation of CHO suspension cells in the wave-mixed single-use Finesse SmartRocker bioreactor with a maximum working volume of 5 L. Using a chemically defined minimal medium, it was possible to produce up to 16.4∙106 cells∙mL-1. SEAP expression was induced by medium exchange and a temperature shift. Maximum SEAP activity of up 33.1 U∙mL-1 was achieved. The results are comparable to cultivations in other wave-mixed bioreactor types. By Nadezda Perepelitsa, Stephan C. Kaiser and Dieter Eibl

  2. Cultivation Of CHO Suspension Cells And SEAP Expression In The Finesse Glass Bioreactor
    3/31/2015

    This application note describes the cultivation of CHO suspension cells in the Finesse glass vessel bioreactor having a maximum working volume of 2.0 L. Using chemically defined minimal media cell densities of up to 7.44∙106 cells∙mL-1 were achieved. The SEAP expression was induced by medium exchange and temperature shift. Maximum SEAP activities of up 63 U∙mL-1 were reached. By Stephan C. Kaiser, Katharina Blaschczok and Dieter Eibl

  3. Mass Propagation Of Nicotiana Tabacum Cv. BY‐2 Suspension Cells In The Finesse Smartrocker Bioreactor
    3/31/2015

    This application note describes the mass propagation of Nicotiana tabacum cv. BY-2 (cultivar tobacco Bright Yellow-2) suspension cells in the Finesse SmartRocker bioreactor at laboratory scale. Maximum fresh cell weights of about 351±9 g•L-1, corresponding to packed cell volumes of 74±2 %, were achieved, which shows the applicability of the Finesse SmartRocker bioreactor to cultivate fast growing plant suspension cells. By Nicole Imseng, Stephan C. Kaiser, Nadezda Perepelitsa, and Dieter Eibl

  4. BPC Chambers Selection Gui
    3/30/2015

    This document helps guide you through the key process of chamber selection based on your application and process requirements.

  5. Characterization Of Single-Use BioProcess Container Systems
    3/30/2015

    The trend towards single-use containers and systems in the biopharmaceutical industry has led to a shift of concerns regarding cleaning and sterilization of conventional multi-use containers and systems to those regarding material characteristics and container/content interactions.

  6. HyPerforma Single-Use Bioreactor (S.U.B.) Condenser System Datasheet
    3/30/2015

    The Thermo Scientific™ HyPerforma™ Single-Use Bioreactor (S.U.B.) Condenser System specifically supports the effective use of the HyPerforma 2000 L S.U.B. and is also available as an auxiliary product for all other S.U.B. systems.

  7. Single-Use Bioreactor Turnkey With G3Lite Controller
    3/30/2015

    The all-new redesigned Thermo Scientific™ Single-Use Bioreactor (S.U.B.) tank provides enhanced functionality, ease of use, and efficiency while maintaining interoperability with Finesse G3Lite™ controllers in both the TruBio™ DV and TruBio™ μC platforms. Either of these proprietary platforms is available with this complete turnkey system.

  8. Scale-Up Of Microbial Fermentation Production Without Modifying Existing Procedures
    3/30/2015

    Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/ sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures. By Jason Brown, Paula Decaria, Nephi Jones, and Tommy Smith

  9. One Film For Your Entire Upstream Production: CX5-14
    3/30/2015

    Thermo Scientific CX5-14 film is engineered to meet the most demanding requirements of your bioproduction processes.

  10. Use Bioreactor Turnkey With G3Lite Controller Datasheet
    3/30/2015

    The all-new redesigned Thermo Scientific™ Single-Use Bioreactor (S.U.B.) tank provides enhanced functionality, ease of use, and efficiency while maintaining interoperability with Finesse G3Lite™ controllers in both the TruBio™ DV and TruBio™ μC platforms.

Newsletter Signup
By clicking Sign Me Up, you agree to our Terms and that you have read our Privacy Policy.