Single Use Featured Articles
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Finding The Right Contract Manufacturer
8/18/2008
Finding a suitable contract manufacturer is, perhaps, one of the most viable options. The pharmaceutical company can concentrate effort and money on research and development and marketing, while the contract manufacturer takes care of the manufacturing process, including validation, support for license application and packaging. In addition, outsourcing can be scheduled into the strategic planning of a drug’s lifecycle. During the early development phases, which last years, a partner with the necessary facilities and experience can be sought out and brought onboard. By Vetter Pharma-Fertigung GmbH & Co. KG
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Poster: Enabling Drug Development And Manufacturing With Innovative Single Use Process Monitoring Technologies
7/21/2008
Single use manufacturing systems for production of bio-therapeutics, where the system arrives to the end-user gamma-irradiated and/or otherwise sterile and where all product contact parts are disposed after use, are in high demand due to the large number of biological products in the pipeline and to the requirement for flexibility in manufacture of products for clinical trials and commercial use
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Article: Comparing Shaker Flasks With A Single-Use Bioreactor For Growing Yeast Seed Cultures
2/13/2008
Pichia pastoris is a species of methylotrophic yeast that is widely used for protein expression both in academia and the biotechnology industry. A number of properties make it suited for this task. Pichia has a high growth rate, and it can grow on simple, inexpensive media. It can also be grown in either shaker flasks or bioreactors, which makes it suitable for both small- and large-scale protein production
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Article: Providing Sterility Assurance Between Single-Use And Stainless Systems
As numerous biopharmaceutical manufacturers have gained firsthand experience with the benefits of incorporating single-use systems into their facilities, they are looking to expand use in both up-stream and down-stream applications. This is no surprise as increased volume and diversity of pharmaceutical products is causing manufacturers to design their facilities based on shorter production runs with multiple changeovers. Meeting these demands requires operational flexibility. By John Boehm and Brent Bushnell
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High-Flow Sterile Connectors For Single-Use Applications
Over the past decade, two developments have increased demand for high fl ow-rate connectors: Size advances in single-use bioreactors up to 2000L and the implementation of single-use downstream.
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Most Common Questions About Combination Connectors
This article provides insight on why combination connections are used in single-use bioprocessing and guidance on how single-use systems can be designed to integrate the combination connectors.
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The Benefits Of Genderless Sterile Connectors For Single-Use Applications
Genderless connections are those in which the connector halves are identical in design, thus eliminating the need for different male and female halves to make the connection.
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The Benefits of Single-Use Technology in R&D and Manufacturing - Infographic
This infographic represents how to bridge the gap in automated single-use technology between R&D and manufacturing, and the benefits of using single-use technology.
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Article: Increase Production Efficiencies With Single-Use Transfer Lines
Biopharmaceutical manufacturers are implementing new ways to leverage existing plant infrastructure to enhance process reliability and flexibility. One solution that continues to gain momentum is single-use systems — particularly single-use transfer lines — which can deliver significant value through added flexibility, improved asset/equipment utilization, and increased cost savings.
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How To Boost Profits With Single-Use Powder Transfer In Biopharma
Does your powder system help to eliminate productivity bottlenecks, decrease material waste and the cost of raw materials, and simplify the changeover of the line to new products?